What the Program is about...

Desperate Housewives...Dark comedy drama exploring the complicated reality behind the apparent domestic bliss of a group of housewives in a fictitious American suburb.- www.channel4.com

Mistresses..Drama series about four female friends' marital and extramarital relationships..-www.bbc.co.uk

Similarities & Differences?
Similarities:

• Relationships within a group of mature women

• Drama series

Differences:

• American surburb
• Comedy
  
• Domestic housewives